Hybrid purification of  Isocyanate mixtures with melt crystallization

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Isocyanates are compounds containing the group (-NCO). They react with compounds containing alcohol groups (-OH) to produce polyurethane polymers, which are components of flexible and rigid foams, insulation, thermoplastic elastomers, spandex fibers, industrial adhesives and polyurethane paints. Diisocyanates (a –NCO group at each end of a hydrocarbon) are the raw materials that make up most typical polyurethane products. The most common diisocyanates used today are toluene diisocyanate (TDI) and methylene biphenyl diisocyanate (MDI). The production process for these feedstocks generates undesirable impurities in the form of other isomers and reaction byproducts that must be separated from the final product. Distillation is typically used to remove most of the impurities; however, the isomers are generally difficult to remove due to their similarities with the main product.

In the case of MDI the main isomer is 4,4’ MDI with 2,4’ MDI and 2,6’ MDI as the main impurities. The ratio of the 4,4’ MDI and 2,4’ MDI isomers in the diisocyanate solution will affect the properties of the final polyurethane and mixtures of the isomers as well as pure 4,4’ MDI are commercially desirable products. Suspension-based melt crystallization is an ideal separation process for this mixture. Continuous operation at ambient temperature and pressure provides the lowest energy requirements of any other separation process. The high selectivity of crystallization produces pure 4,4’ MDI as one product in a single step from most industrial feedstock. The reject from the crystallization process is also a common second product. Hybrid crystallization systems coupled with distillation provide a highly efficient purification process for both MDI and TDI that is applicable in grassroots units or as upgrade to existing distillation based units.